Yes, but it depends on the previous contents of the bag. Bags that previously contained fruits, vegetables, breads and dry goods can be washed and reused. Bags that contained raw meats, fish, eggs or un-pasteurized cheese should be discarded after use because they may contain invisible bacteria that will remain after washing. Bags that contained greasy or oily foods should also be discarded, as they may be difficult to clean. FoodSaver® Bags can be washed by hand. Dry completely. They can then be re-vacuumed.